Getting Started with Tirzepatide

Before You Begin

Before starting compounded tirzepatide, your licensed provider will conduct a thorough evaluation that includes:

• Review of your medical history and current medications
• Assessment of whether FDA-approved tirzepatide (Mounjaro® or Zepbound®) can meet your medical needs
• Documentation of medical necessity if compounded tirzepatide is prescribed
• Determination of your starting dose and titration schedule

IMPORTANT: Sprout Health offers compounded tirzepatide, which is prepared by state-licensed pharmacies.

Compounded medications are not FDA-approved. The FDA does not verify the safety, effectiveness, or quality of compounded drugs before they are marketed.

FDA-approved tirzepatide products (such as Mounjaro® and Zepbound®) are available through traditional healthcare providers. Compounded tirzepatide should only be used when an FDA-approved medication cannot meet your specific medical needs.

Your provider will determine if compounded tirzepatide is appropriate for your individual situation.

Your First Shipment

When your medication arrives:

• Inspect the package for damage or signs the medication got too warm
• Verify the label – confirm medication name, concentration (mg/mL), your name, and expiration date
• Refrigerate immediately at 36-46°F (2-8°C) unless otherwise directed
• Review all included materials – injection instructions, dosing information, and disposal guidelines

Dosing Safety

Compounded tirzepatide may be available in different concentrations than FDA-approved products.

Before your first injection:

1. Verify the concentration of your medication (mg/mL) with your prescription
2. Confirm your prescribed dose in milligrams (mg) with your provider
3. Understand the correct volume to draw in your syringe
4. Don’t confuse “units” marked on insulin-style syringes with milligrams (mg)

If you are uncertain about any aspect of measuring or administering your dose, contact your clinician or the compounding pharmacy before injecting.

What to Expect

• Your provider will typically start you at a lower dose and gradually increase it (titration) to reduce side effects
• Nausea is the most commonly reported side effect when starting treatment. It typically improves as your body adjusts
• Follow all dietary and lifestyle guidance provided by your care team
• Do not adjust your dose without consulting your provider

Questions?

• Clinical questions (dosing, side effects, treatment): Contact your clinician through the medical portal
• Non-clinical questions (shipping, billing, portal): 

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